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DonShimoda

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DonShimoda

Re: poorgradstudent post# 22622

Monday, 10/01/2012 1:21:03 PM

Monday, October 01, 2012 1:21:03 PM

Post# of 80490
Although the MTD has not been reached, at least in ALK+ it certainly appears that 113 offers a stronger response and lower tox than LDK378 (which btw showed DLT at 400mg which also happens to be the active dose....not a good thing)

As far as EGFR goes it is too early to know, however, the PK data looked really good to me...especially in the 8L58R and T790M mutations. Your thoughts? http://bit.ly/V6K65V http://bit.ly/O0DRxG
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