Berger may have been referring to the fact that while they plan to run a treatment naive ALK+ cohort (potentially 1st line), in EGFR they are targeting 2nd line pts who are resistant to at least one prior EGFR inhibitor. http://1.usa.gov/UA4RlT
Hopefully we'll learn more tmrw morning but one thing to note is that even in 2nd line EGFR represents about 2X the ROS1 and ALK+ pts.
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