Avid Bioservices Inc (CDMO)

[entdoc]

dia, CP, and wook, good thinking and great researching. IMO the most important concept is understanding "apoptosis", or the normal arc of cellular degeneration and death. The cell membrane structure is composed of many different phospholipids in different ratios, and many of them are in play, or could be in play in this therapeutic strategy. Phosphatidylserine, PS, is one of the more plentiful. Think of a revolving door and an AAA battery with a positive and negative terminal. During normal apoptosis the PS polarity switches and the molecule "flips" or revolve its inside pole to the outside. That PS polarity change is a normal event along the way to cellular death, and is a sign to the garbageman cells of the immmune system that its a routine scavenger job, not an emergency. However, the externalized PS in this case is masking an emergency. Bavi- unmasks the situation. A true whistle-blower. Without going further into the following scenario, which has been done here so many times, suffice it to say that specialized body immune cell are called to the scene to investigate, are able to penetrate to tumor and sample,"photograph/read" its blueprint, determine that it and is not truly "self", and begin to build and reproduce immune cell clones that will fight and reproduce and fight that cancer cell line.