Avid Bioservices Inc (CDMO)

[Thurly]

CP, Don't forget the rat experiment Thorpe related in the NYAS presentation. Rats with a genetic modification that would constantly produce new prostate cancer cells were treated with Bavi. After the planned treatment cycle, Bavi cleared the system and the rats lived on to ripe old ages ... for rats. How could that be?

The immune system learns when bavi unmasks a tumour. The learning isn't unlearned when Bavi clears the body.

Hence, when the rats were cut open after they died of old age, Thorpe discovered the genetic modification caused the body to continuously produce new prostate cancer cells, but the rats' immune systems always recognised the new instances of the cancer and successfully kept the new cancers at bay.

How much of the PS has to be masked to allow the body to learn that a cancer is hiding? I'd guess not all of it. In theory, it would seem, the animal has to live long enough for the immune system to be educated and turn the tide against the cancer.