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Re: None

Saturday, 09/15/2012 1:22:44 AM

Saturday, September 15, 2012 1:22:44 AM

Post# of 345868
I see a lot of us leaning on Garnick's statement re: "Having personally been involved in the evaluation of over 30 Phase II trials over my career, none of which ever achieved statistical significance, including many of today's blockbuster biotech products" A word of caution:

http://investorshub.advfn.com/boards/read_msg.aspx?message_id=79417508&txt2find=garnick

I was at Genentech for 9 of his 17 years, and was in clinical development, not a dept mgr of regulatory(regulatory had no role in analysis of trial data)

I can think of 10+ ph 2 trials at genentech that reached statistical significance during his time. Why would he say that?


and

http://investorshub.advfn.com/boards/read_msg.aspx?message_id=79419569

1 of the original 3 avastin ph 2 studies were stat sig
The lucentis ph 2 in AMD was stat sig
xolair ph 2 was stat sig


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