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Re: exwannabe post# 92274

Friday, 09/14/2012 10:08:34 AM

Friday, September 14, 2012 10:08:34 AM

Post# of 345952
Iwfal and ex,

bavi showed 43% ORR in an open-label, INDIAN NSCLC trial. In the ongoing, MULTICENTERED (inc. USA), open-label PIIb for 1st line NSCLC, the investigator reads recorded 25% ORR.

When it's said that Asians live longer, does that include India and would you think the drop in ORR was related to the shift to a mixed, as opposed to a oure Asian population in the two trials? In other words, would a shift of 18% be in the ballpark of the expected shift moving from pure Asian to a truly mixed population in such small trials?

Understood that we are looking at n=49 in the Indian, open-label trial and that the ability to assess may not permit strong conclusions given the limitations of the trials.

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