Avid Bioservices Inc (CDMO)

[RRdog]

Entdoc,

Completely agree with your ideas about "radiation".

Thorpe at NYAS was very clear in private Q and A that he thought radiation was "far" more effective in exposing PS to the cell surface than any chemo.(BTW--of the chemo he felt the best was doxy)

IMO some form of combo with Bavi and radiation would radically affect the discussion on "dosing". Heretofore, dosing at 1mg or 3 mg is not making a "major" difference. Perhaps, this is because there is only limited (sub optimum) PS being exposed using chemo. If a great deal more PS were exposed using radiation, then the "dosing" issue might become much more important.

One would hope that any "oncology" partner would want to spend serious research dollars in this area or that PPHM will get enough up front dollars to pursue it properly themselves.

Best Regards,
RRdog