Avid Bioservices Inc (CDMO)

[drragmop]

"bavi would train the immune system to respond to any PS on the outside of any cell"

Correct me if I'm wrong, but I have always thought that the immune response is directed at offending (non-self) material, not the PS. I recall that in one or more of the viral studies, the immune effect to that virus persisted long after the bavi would have cleared, but nobody was claiming that residual immunity was effective against all envelope viruses, as would seem to be the case if the immune system operated against the exposed PS.

Isn't it more correct to say that bavi prevents the exposed PS on affected (cancerous and virally infected) cells from triggering that part of the immune system that merely clears away dead matter and does not "learn" anything, and allows (or causes?? - maybe someone can help here) the more powerful part of the immune system (the one that actually learns, makes antibodies, kills cells, and causes inflammation) to go after, and manufacture antibodies to, the non-self (i.e. cancerous) portions of the affected cells, or the virus or virus fragments?

In short, doesn't bavi respond to the PS, which allows the immune system to respond to the real problem?