Avid Bioservices Inc (CDMO)

[Firechief]

FTM, is it possible that the excerpt below, which you highlighted, explains the unexpected results in the ISTs? It seems possible to me, and I wanted to ask if you think so too? The queer IST results slowed my PPHM accumulation, but didn't stop it.

You highlighted: "The delayed separation of curves has been reported in many clinical trials of immunotherapeutic agents, including a
placebo-controlled phase III trial of the autologous active
cellular immunotherapy sipuleucel-T, where the
immunotherapeutic effect on survival was not evident for 8
months [19], and the first phase III trial of ipilimumab, where
separation of the survival curves for patients treated with
ipilimumab alone, ipilimumab plus gp100 vaccine or gp100
vaccine alone, was not observed until 4 months after the
initiation of treatment [20]."