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Re: BTH post# 427

Tuesday, 08/21/2012 11:44:30 PM

Tuesday, August 21, 2012 11:44:30 PM

Post# of 957
bth, where do you come up with this stuff? How could you have any idea they "got the dosing all screwed up with 101"? Where in the world did you come up with a claim like this. What is your expectation of a reasonable time frame for bringing a compound from concept to approval? Just for reference, Roche with all its resources signed their agreement with Immunogen for TDM1 in 2000 and they are now on the verge of submitting for approval which could come any day now, 12 years and countless millions later. They signed the agreement with Curis in 2003 and already have the drug approved for market.

Many other companies with much more resources take far longer to bring drugs from concept through even just to a successful phase 1 than Curis has with 101. Add in the development work they did prior to offloading 0932 to debio and now that is on the verge of a phase 2 in a relatively short period of time. You surely don't have an understanding of the business you claim to be invested in. Everything they do is trial and error learning along the way. If it were easy everyone would be doing it and the success rate wouldn't be as low as it is. A company as small as Curis with the possibility of multiple successes in the future is pretty amazing IMO.

Have mistakes been made? Sure but EVERY biotech company from Curis to Roche have made mistakes. Actually every company no matter the industry or no matter how successful have made mistakes. Ever hear of the Newton from Apple? Somehow they got past it and had a fair amount of success even with the failures. Good management learns from its mistakes. The great thing is the mistakes that management at Curis have made have not caused the company to go out of business like countless other biotechs.
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