Monday, August 06, 2012 7:37:07 PM
Specificity, specificity, specificity.
Where? More focused cancer cell irradiation,
(radiation in the form of tumor-site delivery, ex.: radioactive iodine borne to cancer core by PPHM anti-TNT MAB, Cotara.
And then there's PPHM's MAB Bavituximab, an immunological stimulant. Might encourage permanent cancer immunity.
Specific cancer imaging? Bavi labels it nicely, and appears to be at least as good as current imaging techniques with the added advantage of helping the body fight cancer in several important ways. For cancer imaging imagine Avid, PPHM's wholly owned MAB production company, with its first Bavi-comopany spin-off: "Imaging Immunogens, Inc."
I was involved in some early(1970)cancer immunity human trials during the BCG-vaccine-for-cancer-craze, and hopeful of finding the answer in immunology. Then, as now, I was impressed by the difference between untreated and treated patients, and how important early cancer detection. Smaller tumor means smaller cytotoxing, i.e. Bavi-like immuno-enhancers, and phasing out chemotherapy as detection increases. Meanwhile we're stuck dealing with the side effects of irradiation and chemotherapy. The good news is that we understand the side-effects more and more each year as cancer survivors live longer. There appears to be justification for the increased enthusiasm here for near-term prospects of PPHM. A couple critical assumptions remain to be, uh, "locked up". Optimism though is different than hyperbole, and playing with imaginary riches is just plain fun. Speaking of hyperbole, in addition to PPHMs dynamite pipeline, the best thing about the company is management's [prior] total lack of hyperbole, and now a deluge of upbeat pronouncement and body language uncharacteristically by a mile of this management team.
We longsufferers will never be able to say we were not alerted. Bavi's inventor, Phil Thorpe, PhD, at UTSW (pharm dept) is more convinced (and convincing) than ever. Of great value to PPHM too, and greatly entertaining, is this website whose denizens are extrordinarily well-rounded, informed, and literate. It great fun and informative to be able to follow corporate events with y'all here. Cheers!
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