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Re: entdoc post# 84385

Sunday, 07/22/2012 2:35:55 PM

Sunday, July 22, 2012 2:35:55 PM

Post# of 346000
Entdoc, I think too much is made of this. Rituximab is a chimeric mAb that was approved 15 years ago
and is still going strong. It gained approval two years ago for maintenance therapy for follicular lymphoma.
http://en.wikipedia.org/wiki/Rituximab
I think if bavi + docetaxel is actually working to stop metastasis, as it seems to be doing in second-line NSCLC,
it is working against small tumors already. I think what is going on is that the primary tumors are stable and
the treatment is preventing the small tumors which start in other organs from growing into larger tumors.
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