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Post# of 252493
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Re: jq1234 post# 143923

Thursday, 06/14/2012 10:14:14 PM

Thursday, June 14, 2012 10:14:14 PM

Post# of 252493

There are many examples of Drug candidates fell through big pharmas' hands before.

With clinical data on hand and in an indication that the big pharma is still interested in? I realize it doesn't mean the drug is doomed for failure but, given the foregoing, I think it's, at a minimum, a red flag.

As of Neratinib, well, it is a validated target, GSK's Tykerb was approved many years ago, Boehringer's Afatinib presented really good data recently. The question is whether Neratinib is differentiated from those two.

Perhaps that's just it; maybe PFE doesn't see the drug as sufficiently differentiated from the competition.

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