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Post# of 252274
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Re: biomaven0 post# 142535

Friday, 05/25/2012 12:53:11 AM

Friday, May 25, 2012 12:53:11 AM

Post# of 252274

But their preliminary HR on OS is still very good. Maybe the crossover won't make such a difference because these patients just don't have much time after confirmed progression.



My fear is that HR=0.47 but no statistical significance and no verbiage of "strongly trending" means that not many OS events might have occurred. Since the trial is successful, I assumed all patients with or without PD will be able to crossover (I am not actually sure of this anymore), we might get a higher final HR and still no statistical significance.

I do not question the data and importance of this data for the NSCLC (or CRC) trial. I am not just sure what other investors will do if/when they encounter HR>0.47 at ASCO.

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