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Re: HeavyDutyGeorge post# 80238

Sunday, 05/20/2012 8:50:53 PM

Sunday, May 20, 2012 8:50:53 PM

Post# of 346461
George, I am not sure what you mean here. You have a few facts incorrect. Roche did not buy out Avastin.
Roche had owned 56% of Genentech and then bought up the remaining 44%, so they got Avastin,
along with Rituxan, Herceptin, and all the rest of it. Approval for Avastin for metastatic breast cancer
was withdrawn because it did not extend the lives of patients when examined in a phase III trial.
Avastin had been given accelerated approval for this indication subject to phase III trial results showing
that overall survival was improved. Avastin has failed in some phase III trials for other indications, but
approval was only withdrawn for metastatic breast cancer.
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