Thank you - that clears up my puzzlement. I knew there must be something I was missing in their language.
I assume the target lesions were in fact the biggest original tumors, which may point to the MOA of the drug. The biggest tumors are most likely to be hypoxic, for example, and so perhaps the drug works best in tumor cells that are already stressed.
But anyhow, your observation reinforces my belief that this is not going to be a single-agent drug in this particular subgroup.
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