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Wednesday, 04/25/2012 3:59:49 PM

Wednesday, April 25, 2012 3:59:49 PM

Post# of 251777
EDAP: New treatment for prostate cancer gives 'perfect results' for nine in ten men:

EDAP is the most undervalued biotech I follow. 13 million shares OS trades at $1.88, positive cash flow and will file NDA later this yeat for revolutionary cancer treatment.
This was $10 a few years back on anticipation of US filing and now its almost here.


A new treatment for prostate cancer can rid the disease from nine in ten men without debilitating side effects, a study has found, leading to new hope for tens of thousands of men.

By Rebecca Smith, Medical Editor10:00PM BST 16 Apr 201211 Comments

http://www.telegraph.co.uk/health/health...

It is hoped the new treatment, which involves heating only the tumours with a highly focused ultrasound, will mean men can be treated without an overnight stay in hospital and avoiding the distressing side effects associated with current therapies.
A study has found that focal HIFU, high-intensity focused ultrasound, provides the 'perfect' outcome of no major side effects and free of cancer 12 months after treatment, in nine out of ten cases.

Traditional surgery or radiotherapy can only provide the perfect outcome in half of cases currently.

Experts have said the results are 'very encouraging' and were a 'paradigm' shift in treatment of the disease.
It is hoped that large scale trials can now begin so the treatment could be offered routinely on the NHS within five years.

The National Institute for Health and Clinical Excellence will say in new guidance next week that the treatment is safe and effective and larger scale trials should go ahead.
A larger trial is already recruiting patients and men interested in the treatment should speak to their cancer doctor or GP about being referrred, experts said.
Prostate cancer is the commonest cancer in men with more than 37,000 diagnoses each year approximately 10,000 deaths.

Current treatments include surgery to remove the whole prostate or radiotherapy. Both of which can effectively treat the cancer but often cause side effects such as incontinence and impotence.

However in many men prostate cancer will not progress to a life threatening disease meaning that radical treatment risks side effects unnecessarily. For this reason, research is now focused on reducing side effects.
Focal HIFU involves careful selection of tumours, as small as a grain of rice, within the prostate gland and targeting them with highly focused ultrasound to heat them and destroy them.

The advantage over previous HIFU and other treatments is that damage to surrounding tissue is minimised, meaning there are far fewer side effects.

In the study published in the journal Lancet Oncology, 41 men were treated with focal HIFU. After 12 months, none were incontinent and one in ten suffered impotence.
The majority, 95 per cent, were free of cancer after 12 months.

Dr Hashim Ahmed, who led the study at University College London Hospitals NHS Foundation Trust andUniversity College London, said: “This changes the paradigm. By focusing just on the areas of cancer we reduce the collateral damage to surrounding tissue.
"Our results are very encouraging. We’re optimistic that men diagnosed with prostate cancer may soon be able to undergo a day case surgical procedure, which can be safely repeated once or twice, to treat their condition with very few side-effects. That could mean a significant improvement in their quality of life.

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