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Re: Seanf812 post# 77788

Thursday, 03/29/2012 10:51:07 AM

Thursday, March 29, 2012 10:51:07 AM

Post# of 346475
The Catch-22 of PPHM. The company has a problem. Their flagship drug (Bavi) has a mechanism of action that would theoretically work best when utilized early on in a new cancer diagnosis. Yet the way clinical trials are set up they only seem to test new drugs in populations of late stage cancer patients. I see no getting around this problem. Which is why the company should devote 80% of its remaining resources getting a Bavi based radiopharmaceutical product developed and tested. Forget trying to "cure" people with two feet in the grave, or extend their lives 1.2 months compared to chemo alone. Develop a radiopharmaceutical that can detect micro metastases and make a self sustaining business out of it. Then utilize cash flow to develop a bavi based molecule with a "killer warhead" of an interferon or radioisotope. But serial dilution to keep testing their drug on Stage 4 hopeless cases is proving futile. The company doesn't have much time left before the death spiral. I imagine news of layoffs can't be too far off. Tustin, wake the hell up.
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