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VRML more news (COMTEX) A: Vermillion receives notice of allowance for platelet biomarker
s for cancer ( Datamonitor )
A: Vermillion receives notice of allowance for platelet biomarkers for cancer (
Datamonitor )

Mar 06, 2012 (Datamonitor via COMTEX) --
Vermillion, Inc., a molecular diagnostics company, has received a notice of
allowance from the US Patent and Trademark Office for a patent titled
Platelet biomarkers for cancer.

The patent resulted from collaboration with the late Dr Judah Folkman, a
renowned cancer expert, and identifies three biomarkers that can be used to
assess changes in endogenous angiogenesis in a subject.

Angiogenesis is commonly associated with cancer, and novel therapeutics such
as bevacizumab (Avastin) target angiogenesis to limit tumor recruitment of
blood vessels.

The patented biomarkers, which are associated with platelets, can be used to
measure ongoing angiogenic activity. The patent covers the measurement of
these biomarkers over time and correlating changes in expression with the
changing level of endogenous angiogenic activity. Consequently, this patent
also enables the use of these biomarkers to monitor efficacy of therapy
directed at angiogenic pathways.

"Vermillion is committed to the creation of innovative, effective tests for
cancer diagnosis and patient management," said Dr Donald Munroe, the
company's chief scientific officer. "We believe the addition of this new
angiogenic biomarkers patent to our already extensive IP portfolio could
enable new methods of monitoring disease progression and therapeutic
response."
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