Thursday, August 04, 2005 11:31:47 PM
copied this under ADMIXMAP ....
Once the genome was sequenced, and until DNAPrint™ mined this sequence and built systems for executing this method, genome screening was prohibitively expensive. Mapping relies on, among other things, the accurate measure of Bio-Geographical Ancestry Admixture, which is the blending of heritage within individuals. In human populations, and on a continental level, there are individuals of relatively unadmixed Bio-Geographical Ancestry ("BGA"), such as Sub-Saharan Africans from Nigeria, Europeans from Northern Europe, and East Asians from Northern China and Native Americans from isolated regions of Southern Mexico. In other places, such as the US, there are recently (in evolutionary time) admixed peoples such as African Americans (a blend of Sub-Saharan African and Indo European BGA) and Hispanics (usually a blend of Native American and European BGA). In recently admixed peoples, the DNA is made of a relatively small number of very large blocks. The Mapping method is applied to these populations, using maps of AIMs throughout the genome, allowing pan-genome coverage with as few as 2,000 markers or a few hundred to a few thousand dollars per subject. Other methods of genome scanning cost hundreds of thousands of dollars per subject.
ARE YOU WRONG FROG? --- GEO
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