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Re: Paulness post# 21583

Monday, 08/01/2005 8:40:48 PM

Monday, August 01, 2005 8:40:48 PM

Post# of 64738
Paulness: I like these items also, form Malcolm's most recent shareholder update:
5) Dr. David Weiner (U. Of Penn Med School) is conducting animal studies USING CYGX CELL-FREE PRODUCED SYNTHETIC DNA to test the immunological activity of a DNA Vaccine against smallpox.
6) Under Agreement, CYGX HAS PROVIDED SYNTHETIC DNA to a company to test the immunological activity of a DNA vaccine against Hepatitis B.
7) Under Agreement, CYGX HAS PROVIDED SYNTHETIC DNA to test the immunological activity of a DNA Vaccine against the influenza virus.
I highlight these items because they tell us that CYGX has done something. Not that they plan to, not that they will do something in the future, not they have "engaged" to do so, not that they have "contacts" to do so. They have gone out and actually PRODUCED THE SYN-DNA and have provided it to certain (as yet un-named) companies to test DNA vaccine. This is actual, concrete progress. We will see something come about from this...I'm not sure what at this time...but I think it will happen by the time Dr. Chen goes to Washington in November to talk about our SYN-DNA for Vaccines at the GTCBIO Symposium. They are already making testable amounts of the syn-DNA, enough of it for other companies to test on Vaccines. I surmise that these other companies were already working on DNA Vaccines and want to test the syn-DNA to see whether it works as well or better than their own "fermented" DNA. If it does, the fact that our syn-DNA is going to be significantly cheaper will make it a no brainer for outside companies to utilize our DNA. Any other choice would be business folly.
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