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biopearl

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biopearl

Re: biomaven0 post# 136363

Friday, 02/03/2012 9:42:24 AM

Friday, February 03, 2012 9:42:24 AM

Post# of 253595
A qualified yes in that "normal" stem cells are quiescent in the adult and appear (if I understand it correctly) to divide very infrequently while cancer progenitor cells express high amounts of telomerase (and have very short telomers) that provides the target for imetelstat. Not sure if megacariocytes are an exception as thrombocytopenia is a DLT. bp
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