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genisi

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genisi

Re: dewophile post# 135568

Wednesday, 01/25/2012 2:35:38 AM

Wednesday, January 25, 2012 2:35:38 AM

Post# of 252254
Looked at the few publications they have. They were studying the molecular mechanism of HCV NS3-4A resistance to PIs. So, my guess is they either used their knowledge to design a PI candidate that can overcome resistance or some new molecule that helps circumvent resistance to PIs or some new unrelated MoA to be used in combo with current approved anti virus treatment. I now tend against the first.
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