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Real-time Raman spectroscopy for in vivo evaluation of skin cancers (Invited Paper)
Paper 8207A-27
Time: 11:30 AM - 11:55 AM
Author(s): Jianhua Zhao, Haishan Zeng, The BC Cancer Agency Research Ctr. (Canada) and The Univ. of British Columbia (Canada); David I. McLean M.D., Harvey Lui M.D., The Univ. of British Columbia (Canada) and The BC Cancer Agency Research Ctr. (Canada)

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An integrated real-time Raman spectroscopic system was constructed for in vivo skin cancer diagnosis. Multi-variant statistical data analysis including principal component analysis (PCA), general discriminant analysis (GDA), and partial least squares (PLS) were used for lesion classification. The analyses were divided into three classifications based on clinical interest: (1) to discriminate skin cancers and precancers from benign skin lesions; (2) to discriminate malignant melanoma from non-melanoma pigmented lesions; and (3) to discriminate malignant melanoma from seborrheic keratosis. Our results demonstrated that real-time Raman spectroscopy is a very promising technique for in vivo clinical skin cancer diagnosis.

http://spie.org/app/program/index.cfm?fuseaction=conferencedetail&conference_id=960833&event_id=896186&list=1&abstracts=1