Avid Bioservices Inc (CDMO)

[entdoc]

North4k, short answer,'yes'. It appears that one of PPHM's Bavituximab immunostimulatory MOAs during irradiation therapy is to excites production of specialized scavenger cells which helps eliminate the "logjam" around cancer cells being killed wholesale by irradiation. If a solid cancer is like a stadium full of bad guys, you can imagine the confusion when the gamma/alpha-ray gun start shooting and there are cancer bodies all over the field and bleachers. Bavi facilitates ingress and egress of ambulances to clear the dead cells and cell parts to help focus on remaining live cancerous cells.
Having said that, this "wire" idea is cool, but there are a couple non-sequiturs that limit practical application in most cases. In brief (and there are exceptions all over the place to what I'M going to say here). In general, if a cancer is surgically resectable, it is resected. What's left to put a wire into? If there are micro-metastases, they are usually either not visible, or too small for the naked eye to insert a wire into, or too many of them, etc. The concept is similar to Cotara's principle of hitting cancer from the inside out, and "the wire" could certainly have application in areas we can't get into (ie GBMs deep inside vital brain tissue)but can reach percutaneously. Yada. A big part of the engineering of "the cure" does relate to a safe, cost-effective, specific delivery system. Seems like we're moving right along with PPHM's anti-PS platform in that regard. Cheers!