Here is what happened with AP1903
I have been an investor of Ariad since 1994. Regarding what happened with AP1903, this is what happened.
When Ariad first developed AP1903, we were told that they intended to use it for GVHD. Ariad then proceeded to enter a Phase 1 and when it was finished they reported that the drug was very safe and that they were in the process of planning a Phase 11. Months went by, with no announcement of a Phase 11, but Harvey kept saying that they were planning a Phase 11. I believe that it was about a year and a half, or so, after the announcement of Phase 1 results, that Harvey, in response to a question at a conference, admitted that they were not going to do Phase 11 yet, because the then existing science had not progressed enough to take advantage of the ability of AP1903 to regulate genes.
That is my best recollection
Barry