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Re: NP1986 post# 128326

Thursday, 10/13/2011 12:28:08 AM

Thursday, October 13, 2011 12:28:08 AM

Post# of 252256

Perhaps patients might also need to be tapered off the medication instead of discontinuing it suddenly in order to avoid a rebound effect.



That seems reasonable. Sort of issue where doctors get more experience with a drug.

But the letter does drive home that the drug is not hitting the underlying disease - really only providing symptomatic relief (which is not nothing).

What remains unknown also is how the drug will perform in some of the more prevalent conditions like polycythemia vera.

Peter

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