Sangamo Biosciences Inc (SGMO)

[ZincFinger]

IMHO SGMO's HIV therapy should be fine for children (far better than other approaches)

It takes immune cells removed from the patient and removes their CCR5 receptors which HIV must use to enter the cells.

Because the rest of the patients immnune system is left intact, children treated this way should develop the same pattern of resistance to diseases that they otherwise would (if no HIV and no CCR5 removal).

It would also be better because compliance is not a problem: no need to take huge numbers of pills/day and no frequent injections either. And, of course none of the side effects that current HIV drugs have. I don''t know whether current HIV drugs would have adverse effects on child development but suspect that they might, There should be no problem in that respect with SGMO's HIV therapy either. (IMHO the stem cell branch is the one that would be best)

If you can post on the investorvillage SGMO board adenylyl (by a very wide margin the most knowledgeable (he's a research scientist in the field) could give you a very definitive answer if he's still there (have to be a paid subscriber to post)

I think I have the email address of a couple of posters there. If i can find one I'll see if I can get one of them to post your question there (you can read without a subscription).

Sorry for the late reply - been behind a bit on email etc.