ACT receives new patent for generating hemangioblast cells
Sep 21, 2011 (Datamonitor via COMTEX) -- Advanced Cell Technology, Inc., or ACT, a regenerative medicine company, has received new patent for the company's proprietary method for generating and expanding hemangioblast cells from human embryonic stem cells, or hESCs.
ACT holds an exclusive license to commercialize the patented technology in North America through an agreement with Stem Cell & Regenerative Medicine International (SCRMI), a joint venture between ACT and CHA Bio & Diostech Co, Ltd (CHA Biotech), a South Korean biotechnology company. Hemangioblasts are precursor cells that can generate a broad spectrum of important blood, immune, and vascular cell types, including red blood cells, platelets, blood vessels, and mesenchymal stem cells, which have powerful immune-modulatory effects and can make bone and cartilage among other replacement tissues.
The hemangioblast cells covered by the new patent are highly expandable and have been shown to consistently and reproducibly give rise to a multitude of cells of the hematopoietic (blood) and endothelial (vascular) lineages. A recent scientific publication shows that hESC-derived hemangioblasts can differentiate into functional megakaryocytes and platelets on a large scale. The hESC-platelets displayed features that were indistinguishable from those of normal blood platelets, and participated in both clot formation and retraction in vitro.
"This is the first US patent on the commercial production of hemangioblast cells, and puts another important piece in place for protecting our hemangioblast program and establishing a firm intellectual property position around the therapeutic products we are developing," stated Gary Rabin, ACT's chairman and CEO. "We are steadily moving toward the clinic with several cell therapy products that are manufactured from hemangioblasts. Having robust patent protection around our manufacturing process is an integral part of the equation for securing investment in these programs."
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