From Shkreli's twitter account: EXEL drops dose in clinical trial - this is a disaster - stock should be down 20% this is their only product and evidently the dose they planned is too toxic to give. ~$1bn market cap and their only product. ruh oh more $EXEL... from what i've seen the company has gone from 100 to 60 to 40mg due to tox. the therapeutic index is probably best at 0mg. Subtle.