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Post# of 252758
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Re: ghmm post# 122905

Wednesday, 07/06/2011 7:24:37 PM

Wednesday, July 06, 2011 7:24:37 PM

Post# of 252758
Speaking of Nektar my rss feed picked up a new trial for NKTR-118
http://www.clinicaltrials.gov/ct2/show/NCT01384292

I'm having a hard time keeping track with all the planned trials for this compound so according this list there are 10 trials (one completed):
http://www.clinicaltrials.gov/ct2/results?intr=%22NKTR-118%22

Assessment of Relative Bioavailability of NKTR-118 in Three Formulations in Healthy Subjects
http://www.clinicaltrials.gov/ct2/show/NCT01365000?intr=%22NKTR-118%22&rank=1

Assessing the Pharmacokinetics of NKTR-118 in Subjects With Renal Impairment Compared to That in Subjects With Normal Renal Function
http://www.clinicaltrials.gov/ct2/show/NCT01372826?intr=%22NKTR-118%22&rank=2

Single and Multiple Ascending Dose Study for NKTR-118 and Cross-over Study to Investigate the Effect of Food for NKTR-118 in Japanese Healthy Subjects (Japan SMAD)
http://www.clinicaltrials.gov/ct2/show/NCT01318655?intr=%22NKTR-118%22&rank=3

A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects
http://www.clinicaltrials.gov/ct2/show/NCT01325415?intr=%22NKTR-118%22&rank=4

Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
http://www.clinicaltrials.gov/ct2/show/NCT01323790?intr=%22NKTR-118%22&rank=5

Absorption, Distribution, Metabolism and Excretion (ADME) Study With Single Oral Administration of [14C] NKTR-118
http://www.clinicaltrials.gov/ct2/show/NCT01348724?intr=%22NKTR-118%22&rank=6

Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain
http://www.clinicaltrials.gov/ct2/show/NCT01384292?intr=%22NKTR-118%22&rank=8

Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
http://www.clinicaltrials.gov/ct2/show/NCT01309841?intr=%22NKTR-118%22&rank=9

Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
http://www.clinicaltrials.gov/ct2/show/NCT01336205?intr=%22NKTR-118%22&rank=10
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