Speaking of Nektar my rss feed picked up a new trial for NKTR-118 http://www.clinicaltrials.gov/ct2/show/NCT01384292 I'm having a hard time keeping track with all the planned trials for this compound so according this list there are 10 trials (one completed): http://www.clinicaltrials.gov/ct2/results?intr=%22NKTR-118%22 Assessment of Relative Bioavailability of NKTR-118 in Three Formulations in Healthy Subjects http://www.clinicaltrials.gov/ct2/show/NCT01365000?intr=%22NKTR-118%22&rank=1 Assessing the Pharmacokinetics of NKTR-118 in Subjects With Renal Impairment Compared to That in Subjects With Normal Renal Function http://www.clinicaltrials.gov/ct2/show/NCT01372826?intr=%22NKTR-118%22&rank=2 Single and Multiple Ascending Dose Study for NKTR-118 and Cross-over Study to Investigate the Effect of Food for NKTR-118 in Japanese Healthy Subjects (Japan SMAD) http://www.clinicaltrials.gov/ct2/show/NCT01318655?intr=%22NKTR-118%22&rank=3 A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects http://www.clinicaltrials.gov/ct2/show/NCT01325415?intr=%22NKTR-118%22&rank=4 Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation http://www.clinicaltrials.gov/ct2/show/NCT01323790?intr=%22NKTR-118%22&rank=5 Absorption, Distribution, Metabolism and Excretion (ADME) Study With Single Oral Administration of [14C] NKTR-118 http://www.clinicaltrials.gov/ct2/show/NCT01348724?intr=%22NKTR-118%22&rank=6 Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain http://www.clinicaltrials.gov/ct2/show/NCT01384292?intr=%22NKTR-118%22&rank=8 Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation http://www.clinicaltrials.gov/ct2/show/NCT01309841?intr=%22NKTR-118%22&rank=9 Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation http://www.clinicaltrials.gov/ct2/show/NCT01336205?intr=%22NKTR-118%22&rank=10