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Re: mcbio post# 122872

Tuesday, 07/05/2011 11:56:12 PM

Tuesday, July 05, 2011 11:56:12 PM

Post# of 252581

LXRX's LX4211 is a dual SGLT2/SGLT1 inhibitor ( http://www.lexpharma.com/pipeline/lx4211.html ). I wonder if this news is bearish for their program as well, or maybe their drug is differentiated being a dual SGLT2/SGLT1 inhibitor.



LXRX is the only one who thinks hitting SGLT1 is a good idea. Everyone else is trying to avoid. Isis even made SGLT2 their only pipeline candidate that is competing directly against more advanced small molecules because SGLT2 is such a difficult drug target. Time will tell who is right (if anyone).

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