Here is a 2009 paper in a peer-reviewed ophthalmic journal showing that an eye drop administration of nipradilol gets to the choroid and retina in the back of the eye by diffusion from the front of the eye, in a manner very similar to the squalamine formulation.
LOL—the paper you cited is about a study in rabbits. Did the researchers ask the rabbits to read letters from an eye chart?
Another poster on this board asked you if you had a business connection to OHRP, but you did not reply. Do you?
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”
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