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Re: biomaven0 post# 119571

Sunday, 05/08/2011 4:34:47 PM

Sunday, May 08, 2011 4:34:47 PM

Post# of 252636

It was striking that the two mutations that emerged in practice and were disclosed in the NEJM article were among those listed as possible by Ariad.

I don't know if it should be really striking as predicting patterns of mutations arising during drug therapy using in vitro mutagenesis screen in cells, isn't a new method and has been used before for other drugs.

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