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ANESRI

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ANESRI

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Monday, 05/02/2011 12:25:53 AM

Monday, May 02, 2011 12:25:53 AM

Post# of 18494
Exosomes and Ovarian cancer

Interaction and uptake of exosomes by ovarian cancer cells
BMC Cancer, 03/29/2011


Escrevente C et al. – Exosomes are internalized by ovarian tumor cells via various endocytic pathways and proteins from exosomes and cells are required for uptake. Exosomes are enriched in specific glycoproteins that may constitute exosome markers. This work contributes to the knowledge about the properties and dynamics of exosomes in cancer.Results •Ovarian carcinoma SKOV3 cell line has been shown to internalize exosomes from same cells via several endocytic pathways that were strongly inhibited at 4 oC, indicating their energy dependence

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