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Re: rumit post# 31172

Wednesday, 04/13/2011 3:27:55 PM

Wednesday, April 13, 2011 3:27:55 PM

Post# of 92948
rumit,

Sinclair does have a "miniature swine model" and evaluates "Subretinal Injection, including Stem Cells".
http://www.sinclairresearch.com/Services/Ophthalmic.aspx

Whether the swine model was used for ACT I have no confirmation of that. Below is all I had on file in regards to Sinclair..

(OCT of 2009)
In June 2009 the Company, along with its collaborators published results of the Long-term Safety and Function of RPE from Human Embryonic Stem Cells in Preclinical Models of Macular Degeneration. In parallel the Company entered into a Master Service Agreement with Sinclair Research of Auxvasse, MO to perform a Biodistribution and Safety/Tumorgenicity Study to further support these results.
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=42541514

(April 2010)
The studies were designed to address the FDA’s request for additional data on tumorigenicity and biodistribution. The Company believes that the data will support the FDA granting clearance for the Company to commence the SMD study in humans later this year. The studies were completed in conjunction with Sinclair Research, based in Columbia, Missouri, Charles River Labs, MPI and Althea Labs, which have been the company’s outside independent collaborators on both studies.
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=49341033

Sinclair Research:
http://www.sinclairresearch.com/AboutUs/Default.aspx

Charles River Labs
http://www.criver.com/en-US/AboutUs/Pages/home.aspx

MPI Research: ACTC has been doing business with these folks for a while.
http://www.mpiresearch.com/About.asp

Althea Labs:?
http://www.altheatech.com./




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