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Tuesday, March 08, 2011 12:26:56 PM
The company has squandered its promise because of basic errors in scientific judgement. A minimum of research would have made it obvious that SA was an incredibly complicated indication to attempt to run clinical trials in. Further, the most statistically significant outcome of the trial (i.e. that ampakines disrupted sleep) should have been foreseen, given earlier clinical trials in sleep deprivation, and in ADHD (loss of sleep was the most common side-effect from that trial). Every scientific endeavour has to start with an exhaustive cost-benefit analysis. They skipped this step, and we've paid the price.
This isn't to say that corx management aren't also lousy business people. They've missed every timeline, and handled communications in an absolutely amateurish and unethical manner: if the private channel communications with people on this BB had the remotest connection with reality, they would have been guilty of abetting insider trading.
I've been trying to stay on the wagon, ignoring this miserable company, but I can't take the Rumsfeldian revisionism that has cropped up lately here. Bad luck has played a part in this company's fortunes, it always does in everything. In my opinion though, management ineptitude has played a much more important role.
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