This sums up big pharma, and our partner Merck real well: http://www.minyanville.com/businessmarkets/articles/pfizer-merger-merck-merger-m2526a-stock/2/2/2011/id/32576?camp=syndication&medium=portals&from=yahoo Bigger is not always better in the drug business. Pfizer increased its R&D spending 20% to $9.4 billion last year but has little to show for its efforts. There are no big, new products to replacing aging blockbusters. I'll probably be skewered for saying this, but just think what Ariad could do with a research budget of $9.4 billion in one year..