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Re: glass_half_full post# 5281

Monday, 01/24/2011 10:12:19 PM

Monday, January 24, 2011 10:12:19 PM

Post# of 80490
Thanks Glass_half_full


I also found the article interesting, and in fact interesting for another Ariad related reason.

I have been investing in Ariad since 1994, when I had to read the original prospectus as part of the information I needed to represent a client in an Ariad related legal matter. More than the foregoing I can't divulge.

Now that the foregoing has been stated, needless to say I have followed the company very closely and remember many events involving Ariad and many statements made by management. I remember when their very first drug, AP1903 was first discussed and went through it's clinical Phase 1. I remember when Ariad was working on a method to inject drugs, such as Insulin, into an individuals muscle and it would remain there for an extended period of time, and when the individuals sugar level dictated a need for insulin, Ariad was developing a pill to give the patient that would cause a release of enough insulin to deal with the patients need. In fact, Ariad actually had a monkey (or several) in whose muscle the insulin was injected and Ariad, from time to time, would announce how long the insulin was still bunched and reamining in the muscle, in tact. Last I remember was that they were able to keep the insulin in the monley's muscle for several years. Of course, if this method was ever fully developed, they could have put it to use for many different drug needs to be released into the body by simply taking a pill not an injection. Morphine, comes to mind immediately etc.

Now back to the point I want to make about this very interesting article, and I hope some Ariad old-timers might also remember this and confirm what I am about to say. I can't remember the year, but I do recall it was at least 10 years ago, or more and it was about the time that Ariad changed it's direction to dedicate the company to developing only cancer drugs, and in effect, discontinuing the drugs and systems I discussed above. I vividly remember HB discussing the cancer drugs that Ariad was developing and talking about a drug that would treat cancer that had metastersized, and or prevent cancers from metastersizing. Could it be that Ariad knew 10, or more years ago, what the scientists in England are now reporting? Or could it be that Ariad is working on a drug to do what HB said way back then? Hmmmmmm



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