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Re: bladerunner1717 post# 5221

Saturday, 01/22/2011 7:44:55 PM

Saturday, January 22, 2011 7:44:55 PM

Post# of 80490
For those that missed it, this is the essence of the last post:

The Johns Hopkins team also found that 14 percent of the samples studied contained mutations in a gene family called mTOR, which regulates cell signaling processes. Papadopoulos says that patients with tumors containing such alterations in the mTOR pathway could be candidates for treatment with mTOR inhibitor drugs.

"This is a great example of the potential for personalized cancer therapy," says Hruban. "Patients who are most likely to benefit from a drug can be identified and treated, while patients whose tumors lack changes in the mTOR pathway could be spared the side effects of drugs that may not be effective in their tumors

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