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BTH

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BTH

Re: rkrw post# 4350

Sunday, 12/26/2010 6:53:32 PM

Sunday, December 26, 2010 6:53:32 PM

Post# of 80490
Let me rephrase:

I don't think Ridaforolimus is a great drug in sarcoma. I think the evidence to date of overwhelming efficacy in mTOR inhibitors (including Rida) in sarcoma has been meager, at best.

As I have stated here many times, I think mTOR inhibitors will find their greatest success in combination with other targeted therapies.

The Phase 2 sarcoma trial Ariad ran was....how do I say this.... "suspect" at best.

I would like to hear your comments.

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