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Post# of 252498
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Re: bladerunner1717 post# 110171

Monday, 12/06/2010 1:24:47 PM

Monday, December 06, 2010 1:24:47 PM

Post# of 252498
ARIA etc...

>Does this raise a red-flag on Bosutinib?<

I think I should clarify that I'm not so much as afraid of bosutinib as concerned about the speed at which ariad can bring their drug to earlier treatment stages.

My pie-in-the-sky dream is that the next trial ARIA starts tomorrow is a head to head trial against imatinib / nilotinib / dasatinib (investigator's choice) in T315I mutation bearers only.

That could reasonably get ponatinib up to a part of the first line, and then ariad could have a reasonable claim with docs that if they don't have a mutation status report on their patients that they're better off starting them all on ponatinib.

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