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Re: gfp927z post# 35013

Friday, 12/03/2010 3:08:03 PM

Friday, December 03, 2010 3:08:03 PM

Post# of 50172

Varney said there weren't any suitable animal models for SA.

Actually there are (paraphrasing from "Cardiovascular consequences of sleep-disordered breathing: contribution of animal models to understanding of the human disease" dematteis et al., 2009) : studies have been carried out in the english bulldog (Hendricks, 1987), obese miniature pigs (Lonergan, 1998), spontaneously hypertensive rats (Carley et al. 1998, 200). Quoting directly from the paper: "Several of these models have proven useful for testing drugs to prevent obstructive and central apneas (Carley and Radulovacki 1999; Carley et al. 1998; Veasey et al. 1996, 1999, 2001)."
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