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Re: jq1234 post# 108923

Monday, 11/15/2010 5:25:50 AM

Monday, November 15, 2010 5:25:50 AM

Post# of 252903
Note that this review is on neuropsychiatric SLE (NPSLE) and looks at the increased immunoglobulin index, which suggested autoantibodies can be synthesized intrathecally within the brain. In NPSLE the BBB can be (at least transiently) damaged but it is still not clear if these antibodies passively diffuse from the peripheral blood or are synthesized by leukocytes inside.

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