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Monday, October 04, 2010 3:20:24 PM
In fact, no antiviral will be developed with mice. This is common knowledge. The SCID mice are not widely used. There are no relevant enzymes in these mice that will mimic human infection. Notice how I won't stoop to making fun of you.
Let me repeat. Mice are lacking important enzymes that make them useful for preclinical antiviral studies. The SCID mouse is no different. It's been this way since 1950, including in 1987 when HAART was developed. That's why I picked that paper. Folks developing antivirals STILL don't use mice.
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