Your assertion that one can’t make unscientific comparisons across clinical studies because “it’s not allowed in the real world” is reminiscent of the argument put forth by Eyetech about five years ago to justify its sales projections for Macugen in the face of superior clinical data for Lucentis.
There never were any head-to-head studies of Macugen vs Lucentis, but that didn’t save Macugen from irrelevance and ultimate extinction.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”
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