Biotech Values

[poorgradstudent]

I think that objective responses can be reliable markers of survival provided that they are high enough. So in that YMI example, if you're doubling objective responses to well north of 70%, then it is reasonable, in my opinion, to speculate on a survival benefit.

On the contrary, I don't think a 10-15% objective response rate as a monotherapy is a reliable indicator of a survival benefit.

I prefer to be a little more conservative. Everyone has their own area of comfort.

good luck!