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Re: genisi post# 97510

Sunday, 06/20/2010 6:10:06 PM

Sunday, June 20, 2010 6:10:06 PM

Post# of 252422
The hard and timely part in this game is designing the expression cassette that contains the vector and cDNA of interest. This part is pretty much the same for all players GENZ,PLX or iBio. Inserting this construct into agrobacteria and then infecting plants instead of inserting directly to cell culture might be a bit more rapid but then extracting from a whole plant instead of cells is longer. So, every system has its own pros and cons but saying iBio's is more versatile simply isn't correct



Putting genes into expression cassettes (if the cassettes already exist and work, like the iBioLaunch vectors do) is fast and easy, especially now that whole genes can be synthesized from scratch rapidly and cheaply by any number of high-quality service providers.

Extracting and purifying proteins from plant tissue instead of cultured cells is not more difficult or longer. I don’t know where that concept comes from, but it is incorrect, and has been proven incorrect not only by iBio and Fraunhofer, but also by other groups working with plants.

iBio’s system is much more versatile than cell culture systems or any approach that requires creation, selection and stabilization of transgenic organisms of any type.


I can't go into it anymore on the board but I wanted to respond.

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