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Re: geocappy1 post# 50895

Friday, 05/21/2010 8:47:23 PM

Friday, May 21, 2010 8:47:23 PM

Post# of 346670
Other thoughts while pulling weeds. A paradigm shift? If Bavi does not completely knock Avastin out of the treatment box, there is an excellent case for trying the two together, and that means adding a bit of Bavi to all treatment regimens. We already know it is an irradiation enhancer. We've established that it enhances standard chemotherapy. Add it to treatment regimens for ALL solid cancers? That's big. This is an excellent example of why so much time and money are spent at the lab bench and in lower animal. Remember that? All the complaints? Imagine if we had no idea about MOA, and thought for instance that Bavi and Avastin work identically. I agree that side-effect profile is probably still okay. It sounds like a lot at first blush, but there was a low drop-out rate, and investigators must report every queasy stomach.
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