Oncolytics Biotech Inc. (ONCY): Reolysin in combo with irinotecan shows...

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Oncolytics Biotech Inc. (ONCY)

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Re: surf1944 post# 168

Wednesday, 04/14/2010 11:09:09 PM

Wednesday, April 14, 2010 11:09:09 PM

Reolysin in combo with irinotecan shows synergistic anticancer activity in colorectal cancer cell lines – AACR 2010 Abstract #1773

http://media.integratir.com/T.ONC/ppt/1773_Sanjay_Colorectal_irinotecan.pdf

Research at the Ludwig Institute of Cancer Research in Melbourne Australia shows synergistic anticancer activity in colorectal cancer cell lines," covers research done in vitro into a novel therapeutic approach for treating patients with colorectal cancer tumors that harbor a mutation in the Kras oncogene that have failed first line therapy.

The investigators found that when REOLYSIN was combined with irinotecan, there was evidence of synergistic cytotoxicity in seven of eight tested cell lines and concluded that the combination of REOLYSIN and irinotecan is synergistic in colorectal cancer cell lines, including those with Kras mutation, and is worthy of exploration in human patients.

The poster is scheduled to be presented on Monday, April 19, 2010.

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